When resin and hardener mix, they undergo an exothermic (heat-releasing) reaction. In thin coats this heat dissipates quickly. In deep pours, the surrounding resin acts as insulation — trapping heat in the center of the mass.
The risk is proportional to both depth and batch volume. A deep pour in a narrow mold is safer than the same depth in a wide, flat vessel — the surface-area-to-volume ratio matters. Always check your product's maximum recommended depth AND batch size.